Will be in San Diego on Monday and Tuesday, staying at the Omni on L street.
Any recs for bars, restaurant and maybe a brewery tour?
San Diego Beer Co - 6th and Broadway - relatively new and very good in my opinion
Mission Brewery - 14th and L - I personally wasn’t impressed with the beer but the place was great
Monkey Paw - 16th and F - I wasn’t there very long but really liked it. Pretty small and I don’t think a tour would be worth it. I think they had some really good guest taps as well and have done some collabs with stone.
Coronado Brewing - I think they have a brand new tap room but I am not sure where it is
I think the White Labs Tasting Room is a must for a homebrewer:
Check out Hess Brewing. They’re making a lot of headlines. Just got awarded San Diego’s best Brewery in some contest I read about. The brewer (Nate) from Rogue’s Eugene location was headhunted to build their new brewery (30bbl I believe) They started with a Nano and are reported to be doing good things. They’ve got a pretty entertaining blog on their Nano start up that goes back to the beginning if you’re curious about them.
Paul, if you go there and see Nate, tell him I said to get a haircut! 
Hess was good, though they had the cloudiest Kolsch I’d ever seen when we went to the nano on the NHC tour.
There’s Alesmith and Ballast Point for excellent breweries with tours. Coronado has good beer and is a fun ferry trip to take. Toronado and other bars on 30th street are good places for beer.
http://sandiego.taphunter.com/beer/Russian-River-Pliny-The-Elder
http://beermapping.com/maps/citymaps.php?m=sandiego
A few links to get you going.
Hess is only operating the nano still- good beer. Societe, Alpine, Rough Draft, Green Flash, Alesmith are a few of my favorites. Stone has an awesome setting and 20 plus beers on tap that are not theirs-have actually gone and not had any of theirs.
Toranado and Hamiltons have great selections.
Unfortunately Monday and Tuesday a lot of tasting rooms are closed 
Good recommendations. I can add Pizza Port Ocean Beach, which is not too far.
+1 on White Labs. Unfortunately, Chris was not there when I visited. Ale Smith is right down the street so go there too. I’m sure it’s been mentioned but Stone and Port/Lost Abbey are worth the drive to Escondido. Green Flash was probably my favorite, though.
Also if you are in downtown SD go to a little place called the Tin Fish. It’s one block from the Padres stadium. Great fish tacos and fries! Also, Anthony’s on Harbor Dr. is a local seafood institution. I’m from CO so any fresh fish is pretty much mindblowing!
White Labs tasting room should be a visit for every home brewer. VERY educational and tasty. We liked the Toronado also, good food and beer.
I’m going to be in San Diego for work most of next week. The White Labs tasting room is only 6 miles from my hotel so I’ll definitely be checking that out.
made it to Toronado, Stone Brewing and Lost Abbey. All of which were amazing, particularly having Stone’s Enjoy By fresh on tap (less than 5 days old). I think Enjoy By unseats Pliny for my top IIPA.