Dozens more types of lager possible due to yeast breeding

Interesting work regarding new lager strains.  This article highlights new breeding done on lager yeasts performed by a group of Belgian scientists.  http://www.mirror.co.uk/news/uk-news/dozens-more-types-lager-possible-6516345

Bummer, couldn’t get the actual article to open.

I think you have to answer a couple of questions to view the article - I’ve got it saved as a pdf file if you can’t access it.

Can you copy and paste as a post?

It opened for me. Good read but not a lot of details yet. I would say they are years away from production scale. Article seems written for beer people by non beer people. The resulting beer tasted “great” no descriptors

And I wonder what difference it will really make?  Of course, no one will know until these strains are produced and tested on a wider scale, but there’s much less variation in lager yeasts than in ale yeasts.  I wonder what kind of new flavors can be produced?

I saw the use of the word “breed”. How do you actually breed yeast? Wouldn’t it be mutations,  or GMO?

I’m with you on this. The great thing about all the new hop varieties coming to market is that there are all these new flavors that everyone wants to use in their beers. For lager yeasts, I can’t really imagine I’d want something that produces new flavor profiles.

Now for Belgian/English/Brett/etc. strains, I’m all in.

Jim, yeast can reproduce two different ways.  The first way that a yeast cell can reproduce is by budding a new daughter cell.  The scientific term for this type of reproduction is mitosis.  Mitosis is asexual reproduction. The second type of reproduction is meiosis, or sexual reproduction.  During meiosis, a cell doubles its DNA and then splits the doubled DNA between four spores, each of which contains half of the mother cell’s DNA. These spores are known as haploid cells they have half of the mother cell’s chromosomes.  The four haploid cells are divided into two a cells and two α (the Greek letter for alpha) halpoid cells.  The a and α cells are basically different sexes, which means that an a cell can mate with an α cell, forming a new diploid cell, basically, the same process that happens when a sperm cell (haploid cell) fertilizes an egg (haploid cell).

Meiosis in brewing strains is rare due to the polyploid nature of brewing yeast. Many strains are triploids.  Triploid strains are basically sterile due to the difficulty of undergoing meiosis.  Tetraploid strains have an even number of sets of chromosomes, but many brewing strains are not perfect tetraploids.  They are what are known as aneuploids.  Aneuploidy in yeast means that the total number of chromsomes is not evenly divisible by 16.  The strains within the Frohberg  (allotetraploid) and Saaz (allotriploid) families of lager yeast that have been sequenced all exhibit aneuploidy.

The lack of genetic diversity in lager yeast is due to fact that Frohberg and Saaz families are from one or two hybridization events (the number of hybridization events is a debated topic).  Many modern scientists question brewing scientists did not inadvertently discard other hybrids during the early days of pure cultures.  The differences in lager strains today are the result of selective pressure

Awesome, thanks Mark. Slightly deep end for me, but the take away is great. I learn something every day here.