Low or high biotransformative yeast in a stout?

i do not have much experience with intentionally using highly biotransformative yeasts with large amounts of hops (dry hops, right?)

would there be any positives or negatives or certain outcomes to using a yeast rated as “biotransformation: high”?

normally ive used cali ales or english ale yeasts for stouts, which are both described as low in this regard.

Thoughts?

For my tastes, biotransformation would not be suitable in stout

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